Parkinson’s Disease

posted in: Neurodegenerative | 0

Parkinson’s disease, dopamine and Neira substance.

Elderly Parkinson's disease

Parkinson’s disease is characterized by neurological disorder due to lack of dopamine. Obviously, this weakens the muscles of the face, neck and throat, causing pain and fatigue and makes speech difficult. The tremors are shaken and uncontrolled movements occurring in the arms, legs and hands. On the other hand, this can start affecting one side of the body and progress to the other. In short, it can be difficult for a person with Parkinson’s disease to move, walk and freely. No doubt it may be that when walking, drag your feet, and take small and careful steps.

Degeneration of the Nigra Substance. Dopamine first, is a neurotransmitter chemical of the central nervous system. Among the most important functions of dopamine is that of regulating motor activity (movement). Dopamine is produced in different parts of the brain, mainly in the substantia nigra, in the area of the midbrain.

In patients with Parkinson’s disease dopaminergic neurons degenerate and die, causing the loss of voluntary movements. Obviously as the neurons of the substantia nigra disappear, a substance called dopamine is no longer produced. As already mentioned, it acts as a neurotransmitter, capable of transporting information from one group of neurons to another. This is through chemical and electrical mechanisms. Dopamine is responsible for transmitting information from the substantia nigra to other areas of the brain.

 

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